Radon Biomonitoring and microRNA in Lung Cancer

Radon and lung cancer.

Lung cancer is the leading cause of cancer-related deaths worldwide. Radon exposure is the second leading cause of lung cancer, following tobacco smoke. Radon is not only an independent risk factor; it also increases the risk of lung cancer in smokers. Numerous cohort, case-control, and experimental studies have established the carcinogenic potential of radon. The possibility of radon having a ...

In Focus: Radon and lung cancer

In the European Union lung cancer death is the most common cause (circa 20%) of total cancer deaths. For 2006 it is estimated that 236,000 lung cancer deaths occurred in the EU 25 with the majority of these being due to active cigarette smoking. From the pooling of 13 residential radon epidemiological studies in 9 EU countries it has been estimated that about 9% of lung cancer deaths may be due...

Re: "Residential radon gas exposure and lung cancer: the Iowa Radon Lung Cancer Study".

Exposure to high concentrations of radon progeny (radon) produces lung cancer in both underground miners and experimentally exposed laboratory animals. To determine the risk posed by residential radon exposure, the authors performed a population-based, case-control epidemiologic study in Iowa from 1993 to 1997. Subjects were female Iowa residents who had occupied their current home for at least...

Radon and lung cancer in the American Cancer Society cohort.

BACKGROUND Case-control studies conducted in North America, Europe, and Asia provided evidence of increased lung cancer risk due to radon in homes. Here, the association between residential radon and lung cancer mortality was examined in a large-scale cohort study. METHODS Nearly 1.2 million Cancer Prevention Study-II participants were recruited in 1982. Mean county-level residential radon co...

Radon daughter exposure and lung cancer.